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VISOMITIN® Eye Drops - SKULACHEV ION SKQ1
10 ml
VISOMITIN® Eye drops based on Skulachev ion SkQ1 is effective for dryness and discomfort in the eyes. Visomitin is used to treat the initial stage of age-related cataracts and dry eye syndrome. Visomitin has antioxidant and keratoprotective effects. Visomitin® is a mild and therefore slow-acting drug.
SkQ1 is a mitochondria-targeted antioxidant that neutralizes free radicals at the site of their formation. SkQ1, thanks to a proven reduction in the activity of free radicals in mitochondria at the cellular level, interrupts the aging program.
Mitotech is developing several drug formulations of SkQ1 covering a variety of therapeutic areas and methods of administration. The most advanced SkQ1-based drug product is Visomitin® which reached Phase III stage in the U.S. for Dry Eye Disease. Visomitin® received marketing approval for Dry Eye Disease in Russia. Multifactorial nature of Dry Eye made this indication a perfect target for SkQ1 as molecule’s mechanism of action addresses gland tissue degeneration, cornea/conjunctiva healing rate and inflammation at the same time.
To combat excess free radicals, special substances are traditionally used - antioxidants. However, the experience gained to date with their use in clinical practice indicates the low efficiency of conventional antioxidants. There are several reasons for this, but one of the most important is that drugs do not penetrate the mitochondria. "Skulachev's ions", on the basis of which the active ingredient of the drug Vizomitin® was created, have unique properties: when entering cells, they are targetedly accumulated in mitochondria. Visomitin® is the world's first registered antioxidant targeting mitochondria.
Indications for use:
As part of complex therapy:
- Symptoms of dry eye syndrome / corneal-conjunctival xerosis (poor tolerance to wind, conditioned air, smoke, foreign body sensation, pain, burning, dry eyes, floating visual acuity, lacrimation, redness of the eyes in the area not covered eyelid).
- Symptoms of the initial stage of age-related cataracts (gradual blurring and decreased visual acuity).
Ingredients:
The active substance of VISOMITIN® Eye drops is plastoquinonyldecyltriphenylphosphonium bromide (PDTP)0.155 μg;
Excipients: Benzalkonium chloride 0.1 mg, hypromellose 2 mg, sodium chloride 9 mg, sodium dihydrogen phosphate dihydrate 0.81 mg, sodium hydrogen phosphate dodecahydrate 1.16 mg, sodium hydroxide 1 M solution to pH 6.0 - 8.0, purified water 1 ml.
Suggested use:
Symptoms of the "dry eye" syndrome: 1-2 drops of the drug in the conjunctival sac 3 times a day. According to clinical studies, the therapeutic effect is achieved in the first 2-4 weeks of use. The therapeutic effect is persistent when used for 6 weeks. If there is no effect during the first 2 weeks of treatment, a specialist examination is required.
The initial stage of age-related cataract: 1-2 drops of the drug into the conjunctival sac 3 times a day. The duration of the course of treatment is 6 months. The diagnosis of "the initial stage of age-related cataract" must be established by a specialist. If there is no improvement after treatment, or the symptoms worsen or new symptoms appear, you should consult your doctor. Use the drug only according to the indications, the route of administration and the doses indicated in the instructions for use.
One bottle is designed for use 3 times a day, 1-2 drops for 24 days.
Special instructions:
Contact lenses: Visomitin® eye drops contain benzalkonium chloride as a preservative and are not recommended for use when wearing contact lenses. Before instilling eye drops, contact lenses should be removed and put back on no earlier than 15 minutes after using the drug.
The bottle must be closed after each use.
Do not touch the eye with the tip of the pipette while instilling.
The active ingredient of Visomitin® is very sensitive to light: between uses, do not store the bottle in a lighted place!
Storage conditions:
In a dark place at a temperature from +2 to +8°C.
Store the opened bottle in a dark place at a temperature from +2 to +8°C; use within 1 month.
Keep out of the reach of children!
Interaction with other drugs:
There have been no previously reported adverse interactions between Visomitin® and other drugs. If necessary, it can be used simultaneously with other eye drops;
the interval between instillations should be at least 15 minutes.
Contraindications:
Hypersensitivity to the components of the drug.
Children under 18 years of age (no clinical trial data available).
Overdose:
When using the drug Visomitin® in accordance with the instructions, an overdose is unlikely. With excessive use, side effects may increase.
Treatment: symptomatic therapy.
Contains:
10 ml
Guarantee:
100% Original from the MITOTECH (Russia)
Production:
Developed by MITOTECH company together with the Moscow State University named after M.V. Lomonosov based on Skulachev ions.