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Mesotel for face and neck

Base price 21,00 €
21,00 €
  • For anti-age effect
  • To reduce wrinkles appereance
  • To moisturize face and neck skin
  • To increase elasticity of the skin
  • To improve skin texture.

Application method:

Apply a small amount of the liquid in the evening on a previously prepared and cleansed face and neck and rub in with massage movements until the substance is completely absorbed. Apply daily. Course duration - 3 months.


Purified water, propylene glycol, bio-antioxidant complex "Neovitin"®, glycerin, tetrahydroxypropyl phenoxyethanol with ethylhexylglycerin, Perfume, panthenol, lactic acid, rosemary extract, sodium carboxymethyl cellulose, PEG-40 hydrogenated castor oil, citric acid, Trilon.

Main components:

HPE-4 - a new generation of biogenic amines external mesoteraphy

HPE-4 (TNRE - tetragidroksipropil ethylene diamine) by its very nature is derived widespread in aesthetic medicine and cosmetology precursor of acetylcholine - deanol. Acetylcholine precursors when used topically bind to the corresponding receptors on the skin cells (fibroblasts, keratinocytes) and lead to a change in skin texture. HPE-4 belongs to the same group of substances, deanol molecule being double (consisting of 2-amino).

In studies revealed that HPE-4 almost four times more efficient deanol, and twice the volunteers are sensitive to it. This was reflected in the fact that the number of women responded positively to anti-aging HPE-4 (smoothing fine lines and wrinkles, improving skin tone and texture), it was more his anti-aging effect was stronger. It follows that the HPE-4 is much more functional compound than deanol.

At microscopy clearly see the result of the interaction of keratinocytes with HPE-4, which is manifested in the reduction of the area of the latter, and thereby developing a lifting effect. Preclinical efficacy trials HPE-4 conducted in Russia and abroad was based on measuring the electrical resistance of keratinocytes. It is known that the performance of their area are inversely proportional to the resistance those the more cells in the volume, the lower the resistance. Application solution HPE-4 leads to a reduction in the area of keratinocyte growth and resistance. Increasing concentrations of HPE-4 leads to even higher resistance and, therefore, a more pronounced reduction in the area of keratinocytes and increased lifting effect. Consequently for typical HPE-4 dose-dependent effect, which is particularly important in the preparation of cosmetic compositions of a different orientation.

The second important aspect of the action HPE-4 is associated with the effect on the function of fibroblasts, which are in response to its application increases the level of collagen and elastin. A direct consequence of this is to increase the elasticity of the skin.

Of course, every new product on the cosmetics market goes a long way of formation from development to implementation. Historically that the HPE-4 is used worldwide for over 20 years and is in very small concentrations as a neutralizer of acidic substances in the composition of many products for skin care and hair care (for both adults and children). However, only a targeted study of all its effects in the last few years revealed excellent anti-aging properties of the HPE-4, as well as to confirm his gentleness and tolerability of a wide dose range.

Safety HPE-4 has been repeatedly proven both in laboratory animals and in volunteers. Compositions containing the drug at various concentrations for 6 months systematically applied to various areas of the body and, thus, do not cause irritation, sensitization and allergic reactions. Moreover, the HPE-4 is completely safe when applied to the eye area, which also has been confirmed clinically.

Neovitin® - induktor endogenous superoxide dismutase

Neovitin® is a product with strong antioxidant and anti-aging properties, derived from the biomass of ginseng root on the original technology CBW when the RAS "Vita". Designed complex was required experimental studies at the Institute of Toxicology. There were proven its anti, UV-a protective, regenerirueschee, antimicrobial, immunomodulatory and antitumor activities. It also improves skin turgor and the local cutaneous blood flow.

Many biochemical reactions occur in the body by a free radical mechanism, but the influence of the environment and malfunctions own antioxidant system leads to an accumulation of an excess of free radicals. As a result, the body undergoes oxidative stress. As a modern high effective anti-oxidative agents in the modern pharmaceutical industry has long used ginseng cell biomass is cultivated using a patented biotechnology. The fact is that the activity of ginseng biomass is much higher than that of living roots. The process of growing technologically and biomass produces a large number of environmentally friendly raw materials, which in modern conditions is important. The drug derived from the biomass of ginseng root on the original technology provides antioxidant protection of the body by stimulating the production of endogenous superoxide dismutase - one of the main antioxidant systems of the body.

The action of the active components of the complex accelerates production in the body and interferon antioksidant enzymes which inhibit the peroxidation reaction (destruction) of the lipids of cell membranes, strengthen them and thereby increase the resistance of tissues and inhibit premature aging.

The unique anti-inflammatory and regenerative properties of Neovitin®  were confirmed by 11 patents and awarded gold medals RANS I. Mechnikov "For the practical contribution to strengthening health of the nation" and Paul Ehrlich of the European Commission for the academic awards "for outstanding achievements in the field of social and preventive medicine."


Despite the fact that the central component of Mesotels for external use is HPE-4 today impossible to imagine its use as a means of mono. Therefore, in order to influence the maximum possible number of units in the pathogenesis of premature skin aging, we proposed to use in Mesotels for external use the combination of anti-aging complex HPE-4 and Neovitin®. On the one hand, Neovitin® serves here as a booster (amplifier effect) that proved clinically (efficiency HPE-4 increased by 23%). On the other hand, the drug improves the microcirculation of the skin, improves the antioxidant status of the skin and prevent photoaging. In this aspect of the complex HPE-4+ Neovitin® should be regarded as the most successful combination of high-level external components Mesotels, providing the maximum expression of this class of drugs for anti-aging effect.

Other components 

In Mesotels based on complex HPE-4+ Neovitin® laid a number of highly active ingredients and extracts that allow them to work purposefully and effectively on their respective areas of skin.

Mesotel for face and neck contains lactic acid that significantly softens and moisturizes face and neck skin. Its action is complemented by active rosemary extract, which in combination with panthenol improves blood circulation in the skin, has an antioxidant effect, protects cell membranes from damage, stimulates the regeneration of skin cells and slows down the aging process.

Form release: 

50 ml



100% Original from the Scientific and Production Center of Revitalization and Health (Russian Federation)


Scientific and Production Center of Revitalization and Health



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Uniqueness of the company NPCRIZ is determined by the exclusive rights to promote the latest high-performance products of the St. Petersburg Institute of Bioregulation and Gerontology in the fields of medicine, genetics and molecular biology. 

Products are not medicines.

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