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SKULACHEV ION - Controlling the Program of Ageing

skulachev ion cat

THEORY - reactive oxygen species are known to present serious danger for living cells and whole organisms, especially with age.

TECHNOLOGY - SkQ1 reduces reactive oxygen species production inside mitochondria in a controlled and sustainable manner.

RESULTS - Several SkQ1-based drugs targeting various age-related disorders are being developed in our labs.

In 2004, a new substance called SkQ1 was synthesized in the group of professor Vladimir P. Skulachev in the Moscow State University. ” The name SkQ1 was given to the substance as the first representative of a particularly potent class of molecules named “SkQ” – the term introduced by the team to describe molecules containing ion Sk an a quinone.

A part of SkQ1 coined “Skulachev ion” or Sk functions as a molecular “locomotive” or “towing truck” carrying the other part of the molecule – an extremely active antioxidant plastoquinone – into mitochondria. Both theoretical calculations and experimental results showed that SkQ1 is delivered into mitochondria in an extremely targeted and efficient manner. The physics of mitochondrial membrane and the unusual properties of “Skulachev ions” direct SkQ1 into the inner leaflet of the inner mitochondrial membrane with high precision.

molecule

Presence of SkQ1 in mitochondrial membrane enables mitochondria to protect itself from reactive oxygen species (ROS) by breaking chain reaction of lipid destruction. This ability of our molecule to protect cells against oxidative stress plays a very important role in treating patients suffering from various age-related disorders such as cardiovascular diseases, neurodegenerative disorders and various ophthalmic conditions.

Skulachev Ion

MitoVitan® Active - SKULACHEV ION SKQ1

Mitochondrial antioxidant concentrate...

39,00 €
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MitoVitan® Serum - SKULACHEV ION SKQ1

SkQ1 is the active ingredient in...

59,00 €
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EXOMITIN® Hydrogel - SKULACHEV ION SKQ1

Regenerating antioxidant

27,00 €
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VISOMITIN® Eye Drops - SKULACHEV ION SKQ1

Eye drops for dryness and discomfort in...

22,00 €
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ABOUT US

Uniqueness of the company NPCRIZ is determined by the exclusive rights to promote the latest high-performance products of the St. Petersburg Institute of Bioregulation and Gerontology in the fields of medicine, genetics and molecular biology.

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